Driven by the potential to confer sustained therapeutic effects and thereby, facilitate prolonged periods of remission, TIL-based therapies have received significant financial support, and promising leads are poised to soon achieve blockbuster status
Roots Analysis has announced the addition of “TIL-based Therapies Market, 2021-2030” report to its list of offerings.
Given the frequently reported inadequacies of conventional cancer therapies and the growing need for personalized medicine, there is a marked surge in the demand for TIL-based therapies. In addition, the clinical success in this domain is likely to draw in investments that will support ongoing and anticipated therapy development initiatives.
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Key Market Insights
Over 80 TIL-based therapies are currently under development
Close to 55% of the aforementioned candidates are being evaluated in clinical stages (phase I/II and above), while more than 20% therapies are in preclinical and discovery stages. Examples of late-stage clinical candidates include CCRT+TIL, Lifileucel, LTX-315 and TILs, and IOV-2001 and LN-145.
More than 80% pipeline candidates are presently being developed to target solid tumors
T-cell immunotherapy developers were observed to be primarily focused on the treatment of different oncological indications. It is worth noting that 17% pipeline candidates are being developed for the treatment of both hematological and solid tumors.
Partnership activity within this domain has increased at a CAGR of 45%, between 2011 and 2020
The maximum partnerships related to TIL-based therapies were inked in the period 2017-2019. Majority of partnership deals signed within this domain were R&D agreements (33%), followed by technology licensing (20%) and manufacturing (15%) agreements.